Skinceuticals A.G.E. Interrupter Advanced is a multi-corrective cream clinically proven to improve visible signs of accelerated aging by preventing the multi-phase glycation process and supporting collagen integrity. Backed by 15+ years of glycation expertise and formulated with more potent and efficacious ingredients than its predecessor (A.G.E. Interrupter), this next-generation cream goes beyond traditional anti-aging skincare to smooth visible wrinkles, restores firmness, and enhances skin's radiance to counter dull and sallow tone. A.G.E. Interrupter Advanced features a rich, dry-finish texture, is suitable for all skin types and tones, and can be used alone or in conjunction with other corrective treatments and moisturizers.
WHAT IS GLYCATION?
Glycation, a key factor of intrinsic aging, occurs when excess glucose molecules bind to structural proteins, such as collagen and elastin. This multi-phase process is accelerated by external aggressors, including UV and pollution, which cause oxidative stress. As glycation progresses, crosslinking occurs and forms a ladder-like structure, causing collagen and elastin to become rigid and brittle, and resulting in Advanced Glycation End-Products (A.G.E.).
A.G.E.s further damage skin cells, degrading their reparative ability and triggering an inflammatory response.